Sodium Modeling in Renal Replacement Therapies

Hyponatremia in CRRT

Volume of D5W needed to slow down the rate of serum sodium rise in CVVHDF

Dialysate Rate (L/h)

Dialysate Sodium (mEq/L)

Prefilter Replacement (L/h)

Prefilter Sodium (mEq/L)

Postfilter Replacement (L/h)

Postfilter Sodium (mEq/L)

Citrate Rate (L/h)

Citrate Sodium Content(mEq/L)

Other Infused Fluid (L/h)

Na in Other Infused Fluid (mEq/L)

Desired Na (mEq/L)

D5W to give post-filter (mL/h)

• D5W infusion will increase the dose of CVVHDF.
• Check serum Na every 1-2 h, once desired Na is achieved the same formula is used to calculate the next Na target.

Information presented here, including use of the calculator, is strictly for educational purposes and should not be used for any other purpose.