Sodium Modeling in Renal Replacement Therapies

Hypernatremia in CRRT

Volume of 3% saline needed to slow down the rate of serum sodium decline in CVVHDF

Dialysate Rate (L/h)

Dialysate Sodium (mEq/L)

Prefilter Replacement (L/h)

Prefilter Sodium (mEq/L)

Postfilter Replacement (L/h)

Postfilter Sodium (mEq/L)

Citrate Rate (L/h)

Citrate Sodium Content(mEq/L)

Other Infused Fluid (L/h)

Na in Other infused Fluid(mEq/L)

Desired Na (mEq/L)

3% saline to give post-filter (mL/h)

• Infusion will increase the dose of CVVHDF.
• Check serum Na every 1-2 h, once desired Na is achieved the same formula is used to calculate the next Na target.

Information presented here, including use of the calculator, is strictly for educational purposes and should not be used for any other purpose.